W19C (p.Trp19Cys) variant of CYP4F2 (Cytochrome P450 4F2)
W19C (p.Trp19Cys) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
W19C (p.Trp19Cys) variant details
- p.Trp19Cys
- ExAC rs764183403
- TOPMed rs764183403
- gnomAD rs764183403
- Missense
- Variant Prioritization Score for Impact Estimate 0.421
- REVEL 0.50
- CADD 22.70
- PolyPhen-2 0.97
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available