S96F (p.Ser96Phe) variant of CYP4F2 (Cytochrome P450 4F2)
S96F (p.Ser96Phe) in CYP4F2 (Cytochrome P450 4F2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
S96F (p.Ser96Phe) variant details
- p.Ser96Phe
- rs1261522986
- NCI-TCGA Cosmic COSV5000
- TOPMed rs1261522986
- gnomAD rs1261522986
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.22
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.62
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available