R46L (p.Arg46Leu) variant of CYP4F2 (Cytochrome P450 4F2)
R46L (p.Arg46Leu) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
R46L (p.Arg46Leu) variant details
- p.Arg46Leu
- 1000Genomes rs141050546
- ESP rs141050546
- ExAC rs141050546
- TOPMed rs141050546
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.24
- CADD 1.19
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available