R46H (p.Arg46His) variant of CYP4F2 (Cytochrome P450 4F2)
R46H (p.Arg46His) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
R46H (p.Arg46His) variant details
- p.Arg46His
- cosmic curated COSV50002
- 1000Genomes rs141050546
- ESP rs141050546
- ExAC rs141050546
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.22
- CADD 1.09
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available