L99F (p.Leu99Phe) variant of CYP4F2 (Cytochrome P450 4F2)
L99F (p.Leu99Phe) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L99F (p.Leu99Phe) variant details
- p.Leu99Phe
- ExAC rs780223239
- gnomAD rs780223239
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.32
- CADD 2.02
- PolyPhen-2 0.47
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 3.4e-05)
- Structural context available