L4P (p.Leu4Pro) variant of CYP4F2 (Cytochrome P450 4F2)
L4P (p.Leu4Pro) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
L4P (p.Leu4Pro) variant details
- p.Leu4Pro
- cosmic curated COSV50001
- gnomAD rs1161180332
- Missense
- Variant Prioritization Score for Impact Estimate 0.475
- REVEL 0.34
- CADD 17.20
- PolyPhen-2 0.05
- SIFT 0.01
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available