L35V (p.Leu35Val) variant of CYP4F2 (Cytochrome P450 4F2)
L35V (p.Leu35Val) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
L35V (p.Leu35Val) variant details
- p.Leu35Val
- ExAC rs753492444
- gnomAD rs753492444
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.30
- CADD 9.86
- PolyPhen-2 0.13
- SIFT 0.06
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available