L23R (p.Leu23Arg) variant of CYP4F2 (Cytochrome P450 4F2)
L23R (p.Leu23Arg) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
L23R (p.Leu23Arg) variant details
- p.Leu23Arg
- gnomAD rs2089455371
- Missense
- Variant Prioritization Score for Impact Estimate 0.692
- REVEL 0.68
- CADD 21.20
- PolyPhen-2 0.56
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available