L22V (p.Leu22Val) variant of CYP4F2 (Cytochrome P450 4F2)
L22V (p.Leu22Val) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L22V (p.Leu22Val) variant details
- p.Leu22Val
- ExAC rs769961014
- TOPMed rs769961014
- gnomAD rs769961014
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.41
- CADD 5.40
- PolyPhen-2 0.27
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available