L22F (p.Leu22Phe) variant of CYP4F2 (Cytochrome P450 4F2)
L22F (p.Leu22Phe) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
L22F (p.Leu22Phe) variant details
- p.Leu22Phe
- ExAC rs769961014
- TOPMed rs769961014
- gnomAD rs769961014
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.34
- CADD 6.72
- PolyPhen-2 0.04
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available