L21F (p.Leu21Phe) variant of CYP4F2 (Cytochrome P450 4F2)
L21F (p.Leu21Phe) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L21F (p.Leu21Phe) variant details
- p.Leu21Phe
- ExAC rs762975146
- gnomAD rs762975146
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.26
- CADD 7.88
- PolyPhen-2 0.12
- SIFT 0.06
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available