I111M (p.Ile111Met) variant of CYP4F2 (Cytochrome P450 4F2)
I111M (p.Ile111Met) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
I111M (p.Ile111Met) variant details
- p.Ile111Met
- TOPMed rs2089442315
- gnomAD rs2089442315
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.24
- CADD 14.60
- PolyPhen-2 0.19
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available