G26W (p.Gly26Trp) variant of CYP4F2 (Cytochrome P450 4F2)
G26W (p.Gly26Trp) in CYP4F2 (Cytochrome P450 4F2) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G26W (p.Gly26Trp) variant details
- p.Gly26Trp
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.40
- CADD 20.30
- PolyPhen-2 0.99
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available