F60S (p.Phe60Ser) variant of CYP4F2 (Cytochrome P450 4F2)
F60S (p.Phe60Ser) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
F60S (p.Phe60Ser) variant details
- p.Phe60Ser
- ExAC rs765175109
- gnomAD rs765175109
- Missense
- Variant Prioritization Score for Impact Estimate 0.766
- REVEL 0.78
- CADD 24.30
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the South Asian population (allele frequency 0.0001)
- Structural context available