F60L (p.Phe60Leu) variant of CYP4F2 (Cytochrome P450 4F2)
F60L (p.Phe60Leu) in CYP4F2 (Cytochrome P450 4F2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
F60L (p.Phe60Leu) variant details
- p.Phe60Leu
- TOPMed rs2089454172
- gnomAD rs2089454172
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.31
- CADD 9.67
- PolyPhen-2 0.02
- SIFT 1.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available