Y99H (p.Tyr99His) variant of CYP3A4 (Cytochrome P450 3A4)
Y99H (p.Tyr99His) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
Y99H (p.Tyr99His) variant details
- p.Tyr99His
- TOPMed rs1204085771
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- CADD 23.00
- PolyPhen-2 0.20
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available