Y75C (p.Tyr75Cys) variant of CYP3A4 (Cytochrome P450 3A4)
Y75C (p.Tyr75Cys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
Y75C (p.Tyr75Cys) variant details
- p.Tyr75Cys
- Ensembl rs1815665114
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available