Y68C (p.Tyr68Cys) variant of CYP3A4 (Cytochrome P450 3A4)
Y68C (p.Tyr68Cys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
Y68C (p.Tyr68Cys) variant details
- p.Tyr68Cys
- ESP rs59418896
- ExAC rs59418896
- TOPMed rs59418896
- gnomAD rs59418896
- Missense
- Variant Prioritization Score for Impact Estimate 0.5
- CADD 24.00
- PolyPhen-2 0.78
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)