Y53H (p.Tyr53His) variant of CYP3A4 (Cytochrome P450 3A4)
Y53H (p.Tyr53His) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
Y53H (p.Tyr53His) variant details
- p.Tyr53His
- ExAC rs746675088
- TOPMed rs746675088
- gnomAD rs746675088
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- CADD 19.80
- PolyPhen-2 0.14
- SIFT 0.05
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available