V81L (p.Val81Leu) variant of CYP3A4 (Cytochrome P450 3A4)
V81L (p.Val81Leu) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
V81L (p.Val81Leu) variant details
- p.Val81Leu
- gnomAD rs1156523076
- Missense
- Variant Prioritization Score for Impact Estimate 0.0812
- CADD 3.17
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available