V81A (p.Val81Ala) variant of CYP3A4 (Cytochrome P450 3A4)
V81A (p.Val81Ala) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
V81A (p.Val81Ala) variant details
- p.Val81Ala
- gnomAD rs1406701067
- Missense
- Variant Prioritization Score for Impact Estimate 0.551
- CADD 21.10
- PolyPhen-2 0.06
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available