V155A (p.Val155Ala) variant of CYP3A4 (Cytochrome P450 3A4)
V155A (p.Val155Ala) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
V155A (p.Val155Ala) variant details
- p.Val155Ala
- ExAC rs778287319
- gnomAD rs778287319
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- AlphaMissense 0.93
- MetaLR 0.34
- MetaSVM -0.43
- CADD 7.27
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available