V101F (p.Val101Phe) variant of CYP3A4 (Cytochrome P450 3A4)
V101F (p.Val101Phe) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V101F (p.Val101Phe) variant details
- p.Val101Phe
- ExAC rs767064297
- gnomAD rs767064297
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- CADD 13.30
- PolyPhen-2 0.08
- SIFT 0.23
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available