T42K (p.Thr42Lys) variant of CYP3A4 (Cytochrome P450 3A4)
T42K (p.Thr42Lys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data.
T42K (p.Thr42Lys) variant details
- p.Thr42Lys
- TOPMed rs1418008703
- gnomAD rs1418008703
- Missense
- Variant Prioritization Score for Impact Estimate 0.0784
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 0.00048)