T166I (p.Thr166Ile) variant of CYP3A4 (Cytochrome P450 3A4)
T166I (p.Thr166Ile) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T166I (p.Thr166Ile) variant details
- p.Thr166Ile
- ExAC rs755800998
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- CADD 10.80
- PolyPhen-2 0.04
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available