T11I (p.Thr11Ile) variant of CYP3A4 (Cytochrome P450 3A4)
T11I (p.Thr11Ile) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data.
T11I (p.Thr11Ile) variant details
- p.Thr11Ile
- ExAC rs201431447
- TOPMed rs201431447
- gnomAD rs201431447
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- CADD 22.90
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the HGDP:RUSSIAN population (allele frequency 0.02)