S18R (p.Ser18Arg) variant of CYP3A4 (Cytochrome P450 3A4)
S18R (p.Ser18Arg) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
S18R (p.Ser18Arg) variant details
- p.Ser18Arg
- ExAC rs763532571
- gnomAD rs763532571
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- CADD 17.40
- PolyPhen-2 0.17
- SIFT 0.35
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)