S139T (p.Ser139Thr) variant of CYP3A4 (Cytochrome P450 3A4)
S139T (p.Ser139Thr) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data.
S139T (p.Ser139Thr) variant details
- p.Ser139Thr
- ExAC rs776078249
- TOPMed rs776078249
- gnomAD rs776078249
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- CADD 20.80
- PolyPhen-2 0.05
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 9.7e-05)