S139G (p.Ser139Gly) variant of CYP3A4 (Cytochrome P450 3A4)
S139G (p.Ser139Gly) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data.
S139G (p.Ser139Gly) variant details
- p.Ser139Gly
- ExAC rs761096029
- gnomAD rs761096029
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- CADD 23.10
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 7.2e-06)