S116C (p.Ser116Cys) variant of CYP3A4 (Cytochrome P450 3A4)
S116C (p.Ser116Cys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data.
S116C (p.Ser116Cys) variant details
- p.Ser116Cys
- TOPMed rs1563042648
- gnomAD rs1563042648
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- CADD 17.70
- PolyPhen-2 0.16
- SIFT 0.01
- Population evidence available