S100F (p.Ser100Phe) variant of CYP3A4 (Cytochrome P450 3A4)
S100F (p.Ser100Phe) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
S100F (p.Ser100Phe) variant details
- p.Ser100Phe
- gnomAD rs1320368777
- Missense
- Variant Prioritization Score for Impact Estimate 0.745
- CADD 25.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available