R130G (p.Arg130Gly) variant of CYP3A4 (Cytochrome P450 3A4)
R130G (p.Arg130Gly) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R130G (p.Arg130Gly) variant details
- p.Arg130Gly
- ExAC rs778013004
- TOPMed rs778013004
- gnomAD rs778013004
- Missense
- Variant Prioritization Score for Impact Estimate 0.605
- CADD 20.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available