P43S (p.Pro43Ser) variant of CYP3A4 (Cytochrome P450 3A4)
P43S (p.Pro43Ser) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data.
P43S (p.Pro43Ser) variant details
- p.Pro43Ser
- ESP rs367582027
- ExAC rs367582027
- TOPMed rs367582027
- gnomAD rs367582027
- Missense
- Variant Prioritization Score for Impact Estimate 0.751
- CADD 23.20
- PolyPhen-2 0.95
- SIFT 0.01
- Most common in the Ashkenazi Jewish population (allele frequency 0.00058)