P43L (p.Pro43Leu) variant of CYP3A4 (Cytochrome P450 3A4)
P43L (p.Pro43Leu) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data.
P43L (p.Pro43Leu) variant details
- p.Pro43Leu
- ESP rs146568511
- ExAC rs146568511
- TOPMed rs146568511
- gnomAD rs146568511
- Missense
- Variant Prioritization Score for Impact Estimate 0.753
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.3e-05)