P169T (p.Pro169Thr) variant of CYP3A4 (Cytochrome P450 3A4)
P169T (p.Pro169Thr) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P169T (p.Pro169Thr) variant details
- p.Pro169Thr
- ExAC rs763047916
- TOPMed rs763047916
- gnomAD rs763047916
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- CADD 0.13
- PolyPhen-2 0.04
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available