P169S (p.Pro169Ser) variant of CYP3A4 (Cytochrome P450 3A4)
P169S (p.Pro169Ser) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P169S (p.Pro169Ser) variant details
- p.Pro169Ser
- ExAC rs763047916
- TOPMed rs763047916
- gnomAD rs763047916
- Missense
- Variant Prioritization Score for Impact Estimate 0.569
- CADD 0.29
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available