P169A (p.Pro169Ala) variant of CYP3A4 (Cytochrome P450 3A4)
P169A (p.Pro169Ala) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P169A (p.Pro169Ala) variant details
- p.Pro169Ala
- ExAC rs763047916
- TOPMed rs763047916
- gnomAD rs763047916
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available