N49D (p.Asn49Asp) variant of CYP3A4 (Cytochrome P450 3A4)
N49D (p.Asn49Asp) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data.
N49D (p.Asn49Asp) variant details
- p.Asn49Asp
- ExAC rs748023655
- gnomAD rs748023655
- Missense
- Variant Prioritization Score for Impact Estimate 0.566
- CADD 19.20
- PolyPhen-2 0.35
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)