M9V (p.Met9Val) variant of CYP3A4 (Cytochrome P450 3A4)
M9V (p.Met9Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data.
M9V (p.Met9Val) variant details
- p.Met9Val
- NCI-TCGA Cosmic COSV6050
- cosmic curated COSV60500
- TOPMed rs1815999616
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0669
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.64
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)