M89V (p.Met89Val) variant of CYP3A4 (Cytochrome P450 3A4)
M89V (p.Met89Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data.
M89V (p.Met89Val) variant details
- p.Met89Val
- TOPMed rs1474094886
- gnomAD rs1474094886
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- CADD 9.56
- PolyPhen-2 0.05
- SIFT 0.11
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)