M62K (p.Met62Lys) variant of CYP3A4 (Cytochrome P450 3A4)
M62K (p.Met62Lys) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
M62K (p.Met62Lys) variant details
- p.Met62Lys
- ExAC rs778202770
- gnomAD rs778202770
- Missense
- Variant Prioritization Score for Impact Estimate 0.0766
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.94
- Most common in the South Asian population (allele frequency 7e-05)
- Structural context available