M145V (p.Met145Val) variant of CYP3A4 (Cytochrome P450 3A4)
M145V (p.Met145Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
M145V (p.Met145Val) variant details
- p.Met145Val
- TOPMed rs1416086132
- gnomAD rs1416086132
- Missense
- Variant Prioritization Score for Impact Estimate 0.606
- CADD 22.40
- PolyPhen-2 0.59
- SIFT 0.11
- Most common in the REMAINING population (allele frequency 6.6e-05)
- Structural context available