L82V (p.Leu82Val) variant of CYP3A4 (Cytochrome P450 3A4)
L82V (p.Leu82Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L82V (p.Leu82Val) variant details
- p.Leu82Val
- ExAC rs758665522
- gnomAD rs758665522
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- CADD 14.50
- PolyPhen-2 0.52
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available