L3V (p.Leu3Val) variant of CYP3A4 (Cytochrome P450 3A4)
L3V (p.Leu3Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data.
L3V (p.Leu3Val) variant details
- p.Leu3Val
- 1000Genomes rs188389063
- ExAC rs188389063
- gnomAD rs188389063
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- CADD 8.25
- PolyPhen-2 0.26
- SIFT 0.04
- Most common in the 1KG:CEU population (allele frequency 0.0042)