L3P (p.Leu3Pro) variant of CYP3A4 (Cytochrome P450 3A4)
L3P (p.Leu3Pro) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
L3P (p.Leu3Pro) variant details
- p.Leu3Pro
- TOPMed rs1433650597
- gnomAD rs1433650597
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- CADD 20.30
- PolyPhen-2 0.84
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 3.3e-05)