L36V (p.Leu36Val) variant of CYP3A4 (Cytochrome P450 3A4)
L36V (p.Leu36Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L36V (p.Leu36Val) variant details
- p.Leu36Val
- ESP rs370199610
- ExAC rs370199610
- TOPMed rs370199610
- gnomAD rs370199610
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- CADD 13.40
- PolyPhen-2 0.01
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available