L36F (p.Leu36Phe) variant of CYP3A4 (Cytochrome P450 3A4)
L36F (p.Leu36Phe) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L36F (p.Leu36Phe) variant details
- p.Leu36Phe
- ESP rs370199610
- ExAC rs370199610
- TOPMed rs370199610
- gnomAD rs370199610
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- CADD 18.40
- PolyPhen-2 0.57
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available