L22V (p.Leu22Val) variant of CYP3A4 (Cytochrome P450 3A4)
L22V (p.Leu22Val) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data.
L22V (p.Leu22Val) variant details
- p.Leu22Val
- 1000Genomes rs570051168
- ExAC rs570051168
- TOPMed rs570051168
- gnomAD rs570051168
- Missense
- Variant Prioritization Score for Impact Estimate 0.471
- CADD 12.30
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the HGDP:DAI population (allele frequency 0.056)