L19Q (p.Leu19Gln) variant of CYP3A4 (Cytochrome P450 3A4)
L19Q (p.Leu19Gln) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data.
L19Q (p.Leu19Gln) variant details
- p.Leu19Gln
- ExAC rs773224444
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- CADD 24.70
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)