L160P (p.Leu160Pro) variant of CYP3A4 (Cytochrome P450 3A4)
L160P (p.Leu160Pro) in CYP3A4 (Cytochrome P450 3A4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
L160P (p.Leu160Pro) variant details
- p.Leu160Pro
- ExAC rs756730062
- gnomAD rs756730062
- Missense
- Variant Prioritization Score for Impact Estimate 0.616
- CADD 23.40
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available